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Article

Gene Mutation Analysis in 253 Chinese Children with Unexplained Epilepsy and Intellectual/Developmental Disabilities.

PloS one - 1 Jan 2015

Zhang Yujia, Kong Weijing, Gao Yang, Liu Xiaoyan, Gao Kai, Xie Han, Wu Ye, Zhang Yuehua, Wang Jingmin, Gao Feng, Wu Xiru, Jiang Yuwu

Abstract excerpt

OBJECTIVE: Epilepsy and intellectual/developmental disabilities (ID/DD) have a high rate of co-occurrence. Here, we investigated gene mutations in Chinese children with unexplained epilepsy and ID/DD. METHODS: We used targeted next-generation sequencing to detect mutations within 300 genes related to epilepsy and ID/DD in 253 Chinese children with unexplained epilepsy and ID/DD. A series of filtering criteria was...

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PMID: 26544041
DOI: 10.1371/journal.pone.0141782
PMCID: PMC4636363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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