Comparison of environmental risk factors for esophageal atresia, anorectal malformations, and the combined phenotype in 263 German families.

doi:10.1111/dote.12431

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Article

Comparison of environmental risk factors for esophageal atresia, anorectal malformations, and the combined phenotype in 263 German families.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Nov 2016

Zwink N, Choinitzki V, Baudisch F, Hölscher A, Boemers T M, Turial S, Kurz R, Heydweiller A, Keppler K, Müller A, Bagci S, Pauly M, Brokmeier U, Leutner A, Degenhardt P, Schmiedeke E, Märzheuser S, Grasshoff-Derr S, Holland-Cunz S, Palta M, Schäfer M, Ure B M, Lacher M, Nöthen M M, Schumacher J, Jenetzky E, Reutter H

Abstract excerpt

Esophageal atresia with or without tracheoesophageal fistula (EA/TEF) and anorectal malformations (ARM) represent the severe ends of the fore- and hindgut malformation spectra. Previous research suggests that environmental factors are implicated in their etiology. These risk factors might indicate the influence of specific etiological mechanisms on distinct developmental processes (e.g. fore- vs. hindgut...

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PMID: 26541887
DOI: 10.1111/dote.12431

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