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Article

Inflammation as a Driver of Clonal Evolution in Myeloproliferative Neoplasm.

Mediators of inflammation - 1 Jan 2015

Fleischman Angela G

Abstract excerpt

Our understanding of inflammation's role in the pathogenesis of myeloproliferative neoplasm (MPN) is evolving. The impact of chronic inflammation, a characteristic feature of MPN, likely goes far beyond its role as a driver of constitutional symptoms. An inflammatory response to the neoplastic clone may be responsible for some pathologic aspects of MPN. Moreover, JAK2V617F mutated hematopoietic stem and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26538830
DOI: 10.1155/2015/606819
PMCID: PMC4619974

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