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Article

H-RAS mutation is a key molecular feature of pediatric urothelial bladder cancer. A detailed report of three cases.

Journal of pediatric urology - 1 Apr 2016

Castillo-Martin Mireia, Collazo Lorduy Ana, Gladoun Nataliya, Hyun Grace, Cordon-Cardo Carlos

Abstract excerpt

INTRODUCTION: Urothelial carcinoma (UC) of the bladder is a rare entity in the pediatric population, with an incidence of less than 0.4% in patients younger than 20 years. These patients overwhelmingly present with non-muscle-invasive low-grade disease and an indolent behavior. OBJECTIVE: The aim was to determine the source of the different natural history between pediatric population and adults; we hypothesized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26522772
DOI: 10.1016/j.jpurol.2015.08.020

Genes

FGFR3
EGFR
PTEN

Provenance

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