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Article

Different spatial distributions of brain metastases from lung cancer by histological subtype and mutation status of epidermal growth factor receptor.

Neuro-oncology - 1 May 2016

Takano Koji, Kinoshita Manabu, Takagaki Masatoshi, Sakai Mio, Tateishi Souichirou, Achiha Takamune, Hirayama Ryuichi, Nishino Kazumi, Uchida Junji, Kumagai Toru, Okami Jiro, Kawaguchi Atsushi, Hashimoto Naoya, Nakanishi Katsuyuki, Imamura Fumio, Higashiyama Masahiko, Yoshimine Toshiki

Abstract excerpt

BACKGROUND: The purpose of this study was to test the hypothesis that the genetic backgrounds of lung cancers could affect the spatial distribution of brain metastases. METHODS: CT or MR images of 200 patients with a total of 1033 treatment-naive brain metastases from lung cancer were retrospectively reviewed (23 by CT and 177 by MRI). All images were standardized to the human brain MRI atlas provided by the...

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Identifiers

PMID: 26519739
DOI: 10.1093/neuonc/nov266
PMCID: PMC4827044

Genes

EGFR

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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