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Article

Sex differences in the blood antioxidant defense system in juvenile rats with various genetic predispositions to hypertension.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Feb 2016

Horvathova Martina, Zitnanova Ingrid, Kralovicova Zuzana, Balis Peter, Puzserova Angelika, Muchova Jana, Kluknavsky Michal, Durackova Zdenka, Bernatova Iveta

Abstract excerpt

This study investigated the contribution of blood oxidative stress (OS) to the development of hypertension, as well as sex differences in the antioxidant defense system (ADS) in genetic models of hypertension. Nine-week-old normotensive Wistar-Kyoto (WKY) rats, borderline hypertensive rats (BHR) and spontaneously hypertensive rats (SHR) of both sexes were used. Systolic blood pressure (SBP) was determined by...

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PMID: 26510784
DOI: 10.1038/hr.2015.117

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