Article
SAMHD1 Gene Mutations Are Associated with Cerebral Large-Artery Atherosclerosis.
BioMed research international - 1 Jan 2015
Li Wei, Xin Baozhong, Yan Junpeng, Wu Ying, Hu Bo, Liu Liping, Wang Yilong, Ahn Jinwoo, Skowronski Jacek, Zhang Zaiqiang, Wang Yongjun, Wang Heng
Abstract excerpt
BACKGROUND: To investigate whether one or more SAMHD1 gene mutations are associated with cerebrovascular disease in the general population using a Chinese stroke cohort. METHODS: Patients with a Chinese Han background (N = 300) diagnosed with either cerebral large-artery atherosclerosis (LAA, n = 100), cerebral small vessel disease (SVD, n = 100), or other stroke-free neurological disorders (control, n = 100)...
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