Article
Effect of summer daylight exposure and genetic background on growth in growth hormone-deficient children.
The pharmacogenomics journal - 1 Nov 2016
De Leonibus C, Chatelain P, Knight C, Clayton P, Stevens A
Abstract excerpt
The response to growth hormone in humans is dependent on phenotypic, genetic and environmental factors. The present study in children with growth hormone deficiency (GHD) collected worldwide characterised gene-environment interactions on growth response to recombinant human growth hormone (r-hGH). Growth responses in children are linked to latitude, and we found that a correlate of latitude, summer daylight...
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