Article
Estimating Relatedness in the Presence of Null Alleles.
Genetics - 1 Jan 2016
Huang Kang, Ritland Kermit, Dunn Derek W, Qi Xiaoguang, Guo Songtao, Li Baoguo
Abstract excerpt
Studies of genetics and ecology often require estimates of relatedness coefficients based on genetic marker data. However, with the presence of null alleles, an observed genotype can represent one of several possible true genotypes. This results in biased estimates of relatedness. As the numbers of marker loci are often limited, loci with null alleles cannot be abandoned without substantial loss of statistical...
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