Article
Novel association of polymorphic genetic variants with predictors of outcome of catheter ablation in atrial fibrillation: new directions from a prospective study (DECAF).
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing - 1 Jan 2016
Mohanty Sanghamitra, Hall Amelia W, Mohanty Prasant, Prakash Sameer, Trivedi Chintan, Di Biase Luigi, Santangeli Pasquale, Bai Rong, Burkhardt J David, Gallinghouse G Joseph, Horton Rodney, Sanchez Javier E, Hranitzky Patrick M, Al-Ahmad Amin, Iyer Vishwanath R, Natale Andrea
Abstract excerpt
PURPOSE: Non-pulmonary vein (non-PV) triggers and left atrial (LA) scars perpetuate atrial fibrillation (AF) and limit the success rate of catheter ablation. In order to understand the genetic basis of these risk factors, we examined the association of selected single nucleotide polymorphisms (SNPs) with scar and non-PV triggers. METHODS: Four hundred AF patients (67 %male, 62±12 years, LA size 45.3±7 mm,...
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