Whole genome sequencing of fecal samples as a tool for the diagnosis and genetic characterization of norovirus.

doi:10.1016/j.jcv.2015.10.003

Article

Whole genome sequencing of fecal samples as a tool for the diagnosis and genetic characterization of norovirus.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Nov 2015

Bavelaar Herjan H J, Rahamat-Langendoen Janette, Niesters Hubert G M, Zoll Jan, Melchers Willem J G

Abstract excerpt

BACKGROUND: Norovirus is a major cause of gastroenteritis, causing yearly epidemics and hospital outbreaks resulting in a high burden on health care. Detection and characterization of norovirus directly from clinical samples could provide a powerful tool in infection control and norovirus epidemiology. OBJECTIVES: To determine whether next-generation sequencing directly on fecal samples can accurately detect and...

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Whole genome sequencing of fecal samples as a tool for the diagnosis and genetic characterization of norovirus.

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