Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Four Isoforms of Arabidopsis 4-Coumarate:CoA Ligase Have Overlapping yet Distinct Roles in Phenylpropanoid Metabolism.

Plant physiology - 1 Dec 2015

Li Yi, Kim Jeong Im, Pysh Len, Chapple Clint

Abstract excerpt

The biosynthesis of lignin, flavonoids, and hydroxycinnamoyl esters share the first three enzymatic steps of the phenylpropanoid pathway. The last shared step is catalyzed by 4-coumarate:CoA ligase (4CL), which generates p-coumaroyl CoA and caffeoyl CoA from their respective acids. Four isoforms of 4CL have been identified in Arabidopsis (Arabidopsis thaliana). Phylogenetic analysis reveals that 4CL1, 4CL2, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arabidopsis
Share to Arabidopsis Proteins
Share to Coenzyme A Ligases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Plant

Share to Isoenzymes

Share to Lignin

Share to Metabolic Networks and Pathways

Share to Secondary Metabolism

Source

Open in PubMed Open full text

Identifiers

PMID: 26491147
DOI: 10.1104/pp.15.00838
PMCID: PMC4677886

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Four Isoforms of Arabidopsis 4-Coumarate:CoA Ligase Have Overlapping yet Distinct Roles in Phenylpropanoid Metabolism.PMID 26491147Read ↗

Genome-edited rice deficient in two 4-COUMARATE:COENZYME A LIGASE genes displays diverse lignin alterations.Semantic proximity Read ↗

Molecular and Biochemical Characterization of Two 4-Coumarate: Coa Ligase Genes in Tea Plant (Camellia Sinensis)Semantic proximity Read ↗

Mutational analysis of 4-coumarate:CoA ligase identifies functionally important amino acids and verifies its close relationship to other adenylate-forming enzymes.Semantic proximity Read ↗

Silencing of 4-coumarate:coenzyme A ligase in switchgrass leads to reduced lignin content and improved fermentable sugar yields for biofuel production.Semantic proximity Read ↗

Dysfunction of the 4-coumarate:coenzyme A ligase 4CL4 impacts aluminum resistance and lignin accumulation in rice.Semantic proximity Read ↗

A systems biology view of responses to lignin biosynthesis perturbations in Arabidopsis.Semantic proximity Read ↗

Repression of lignin biosynthesis promotes cellulose accumulation and growth in transgenic trees.Semantic proximity Read ↗

Caffeoyl shikimate esterase (CSE) is an enzyme in the lignin biosynthetic pathway in Arabidopsis.Semantic proximity Read ↗

Genome-Wide Identification and Characterisation of the 4-Coumarate–CoA Ligase (4CL) Gene Family in Gastrodia elata and Their Transcriptional Response to Fungal InfectionSemantic proximity Read ↗

Trends in lignin modification: a comprehensive analysis of the effects of genetic manipulations/mutations on lignification and vascular integrity.Semantic proximity Read ↗

Clade classification of monolignol biosynthesis gene family members reveals target genes to decrease lignin in Lolium perenne.Semantic proximity Read ↗

Brown midrib2 (Bmr2) encodes the major 4-coumarate:coenzyme A ligase involved in lignin biosynthesis in sorghum (Sorghum bicolor (L.) Moench).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.