Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients.

Oncotarget - 27 Oct 2015

Wang Rui, Zhang Yang, Pan Yunjian, Li Yuan, Hu Haichuan, Cai Deng, Li Hang, Ye Ting, Luo Xiaoyang, Zhang Yiliang, Li Bin, Shen Lei, Sun Yihua, Chen Haiquan

Abstract excerpt

PURPOSE: To determine the frequency of driver mutations in Chinese non-small cell lung cancer (NSCLC) patients. METHODS: Comprehensive mutational analysis was performed in 1356 lung adenocarcinoma, 503 squamous cell carcinoma, 57 adenosquamous lung carcinoma, 19 large cell carcinoma and 8 sarcomatoid carcinoma. The effect of EGFR tyrosine kinase inhibitors (TKIs) on EGFR-mutated lung adenocarcinoma patients after...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to ErbB Receptors

Share to Kaplan-Meier Estimate

Share to Neoplasm Recurrence, Local

Share to Protein Kinase Inhibitors

Share to Real-Time Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 26486077
DOI: 10.18632/oncotarget.5549
PMCID: PMC4741453

Genes

EGFR
KRAS
ALK
ARAF
BRAF
FGFR3
NRG1
RET
ROS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients.PMID 26486077Read ↗

Genomic characteristics of driver genes in Chinese patients with non‐small cell lung cancerSemantic proximity Read ↗

Prevalence of driver mutations in non-small-cell lung cancers in the People&rsquo;s Republic of ChinaSemantic proximity Read ↗

Genomic Profiling of Driver Gene Mutations in Chinese Patients With Non-Small Cell Lung CancerSemantic proximity Read ↗

Genomic Signature of Driver Genes Identified by Target Next-Generation Sequencing in Chinese Non-Small Cell Lung CancerSemantic proximity Read ↗

[Advances on driver oncogenes of non-small cell lung cancer].Semantic proximity Read ↗

Driver gene alterations in NSCLC patients in southern China and their correlation with clinicopathologic characteristicsSemantic proximity Read ↗

The co-mutation of EGFR and tumor-related genes leads to a worse prognosis and a higher level of tumor mutational burden in Chinese non-small cell lung cancer patientsSemantic proximity Read ↗

[Driver genes and its clinical significance in non-small cell lung cancer].Semantic proximity Read ↗

Genetic profile of non-small cell lung cancer (NSCLC): A hospital-based survey in Jinhua.Semantic proximity Read ↗

Characterization of driver mutations in Chinese non-small cell lung cancer patients using a novel targeted sequencing panelSemantic proximity Read ↗

Pathological Signature and Therapeutic Status of NSCLC Patients with Common or Rare Driver Gene Alterations in North China：A real world retrospective studySemantic proximity Read ↗

Prevalence and Clinicopathological Characteristics of BRAF Mutations in Chinese Patients with Lung Adenocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.