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Article

Relationship between VEGFA polymorphisms and serum VEGF protein levels and recurrent spontaneous miscarriage.

Human reproduction (Oxford, England) - 1 Oct 2013

Almawi Wassim Y, Saldanha Fabiola Lisa, Mahmood Naeema A, Al-Zaman Intissar, Sater Mai S, Mustafa Fekria E

Abstract excerpt

STUDY QUESTION: Is recurrent spontaneous miscarriage (RSM) associated with changes in vascular endothelial growth factor (VEGF) serum levels, and with polymorphisms in the VEGFA gene? SUMMARY ANSWER: Reduced serum VEGF levels, and VEGFA -460T/C (rs833061), 398G/A (rs833068), -583T/C (rs3025020) variants, were associated with RSM. WHAT IS KNOWN ALREADY: Reduced expression of VEGF has been linked with spontaneous...

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Share to Abortion, Spontaneous
Share to Gene Frequency
Share to Genetic Association Studies
Share to Genotype
Share to Linkage Disequilibrium
Share to Neovascularization, Physiologic
Share to Polymorphism, Single Nucleotide
Share to Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 23900206
DOI: 10.1093/humrep/det308

Genes

VEGFA
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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