Article
A Non-Synonymous HMGA2 Variant Decreases Height in Shetland Ponies and Other Small Horses.
PloS one - 1 Jan 2015
Frischknecht Mirjam, Jagannathan Vidhya, Plattet Philippe, Neuditschko Markus, Signer-Hasler Heidi, Bachmann Iris, Pacholewska Alicja, Drögemüller Cord, Dietschi Elisabeth, Flury Christine, Rieder Stefan, Leeb Tosso
Abstract excerpt
The identification of quantitative trait loci (QTL) such as height and their underlying causative variants is still challenging and often requires large sample sizes. In humans hundreds of loci with small effects control the heritable portion of height variability. In domestic animals, typically only a few loci with comparatively large effects explain a major fraction of the heritability. We investigated height...
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