Article
Improved detection of disease-associated variation by sex-specific characterization and prediction of genes required for fertility.
Andrology - 1 Nov 2015
Ho N R Y, Huang N, Conrad D F
Abstract excerpt
Despite its great potential, high-throughput functional genomic data are rarely integrated and applied to characterizing the genomic basis of fertility. We obtained and reprocessed over 30 functional genomics datasets from human and mouse germ cells to perform genome-wide prediction of genes underlying various reproductive phenotypes in both species. Genes involved in male fertility are easier to predict than...
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