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Article

Sparse Modeling Reveals miRNA Signatures for Diagnostics of Inflammatory Bowel Disease.

PloS one - 1 Jan 2015

Hübenthal Matthias, Hemmrich-Stanisak Georg, Degenhardt Frauke, Szymczak Silke, Du Zhipei, Elsharawy Abdou, Keller Andreas, Schreiber Stefan, Franke Andre

Abstract excerpt

The diagnosis of inflammatory bowel disease (IBD) still remains a clinical challenge and the most accurate diagnostic procedure is a combination of clinical tests including invasive endoscopy. In this study we evaluated whether systematic miRNA expression profiling, in conjunction with machine learning techniques, is suitable as a non-invasive test for the major IBD phenotypes (Crohn's disease (CD) and ulcerative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26466382
DOI: 10.1371/journal.pone.0140155
PMCID: PMC4605644

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