Article
Mitochondrial DNA Haplogroup R Confers a Genetic Risk Factor for Intrauterine Adhesion in Han Women Population.
Gynecologic and obstetric investigation - 1 Jan 2016
Zhang Jing, Zhu Libo, Huang Xiufeng, Xu Ping, Chen Zhengyun, Huang Qiongshi, Zhang Xinmei
Abstract excerpt
BACKGROUND: To determine whether a specific mitochondrial DNA (mtDNA) haplogroup is implicated in the pathogenesis of intrauterine adhesion (IUA). METHODS: Peripheral blood samples were collected from 486 women with (case group, n = 154) and without IUA (control group, n = 332) at the Women's Hospital, Zhejiang University School of Medicine. Genomic DNA was extracted from the blood, and the mtDNA haplogroups of...
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