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Article

Diagnostic and Treatment Options for Severe IBD in Female X-CGD Carriers with Non-random X-inactivation.

Journal of Crohn's & colitis - 1 Jan 2016

Hauck Fabian, Koletzko Sibylle, Walz Christoph, von Bernuth Horst, Klenk Anne, Schmid Irene, Belohradsky Bernd H, Klein Christoph, Bufler Philip, Albert Michael H

Abstract excerpt

BACKGROUND AND AIMS: X-linked chronic granulomatous disease [X-CGD] due to hemizygous mutations in CYBB is characterised by invasive bacterial and fungal infections and granulomatous inflammation. Inflammatory bowel disease [IBD] is an additional or isolated manifestation. Allogeneic haematopoietic stem cell transplantation [alloHSCT] is the standard curative treatment. X-CGD carriers are usually healthy but...

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Source

Identifiers

PMID: 26464403
DOI: 10.1093/ecco-jcc/jjv186

Genes

CYBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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