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Article

Mutation screening in dilated cardiomyopathy: prominent role of the beta myosin heavy chain gene.

European heart journal - 1 Apr 2005

Villard Eric, Duboscq-Bidot Laetitia, Charron Philippe, Benaiche Abdelaziz, Conraads Viviane, Sylvius Nicolas, Komajda Michel

Abstract excerpt

AIMS: Familial dilated cardiomyopathy (FDCM) is associated with mutations in more than 10 genes, but genes mutation frequencies and associated clinical features remain largely unknown. Here, we performed a mutation analysis of four genes involved in FDCM in a population of idiopathic DCM. METHODS AND RESULTS: A SSCP and sequencing mutation screening of all the exons coding for beta myosin heavy chain (MYH7 gene),...

Read the complete abstract on PubMed

Topics

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Share to Aged, 80 and over
Share to Cardiomyopathy, Hypertrophic, Familial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Infant

Share to Myosin Heavy Chains

Share to Pedigree

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 15769782
DOI: 10.1093/eurheartj/ehi193

Genes

MYH7
TNNT2
PLN
VCL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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