Epigenetics and assisted reproductive technology

Abstract excerpt

During gametogenesis, the female and male germ cells undergo a process whereby imprinting marks are erased from the genome. During the later stages of germ-cell development, the methylation marks of the female and male germ lines are re-established. A second phase of demethylation of the genome occurs at the time of fertilization, and during development of the early embryo. Assisted reproductive technology...

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