Article
Generation and periodontal differentiation of human gingival fibroblasts-derived integration-free induced pluripotent stem cells.
Biochemical and biophysical research communications - 6 May 2016
Yin Xiaohui, Li Yang, Li Jingwen, Li Peng, Liu Yinan, Wen Jinhua, Luan Qingxian
Abstract excerpt
Induced pluripotent stem cells (iPSCs) have been recognized as a promising cell source for periodontal tissue regeneration. However, the conventional virus-based reprogramming approach is associated with a high risk of genetic mutation and limits their therapeutic utility. Here, we successfully generated iPSCs from readily accessible human gingival fibroblasts (hGFs) through an integration-free and feeder-free...
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