Article
Using Genomics for Natural Product Structure Elucidation.
Current topics in medicinal chemistry - 1 Jan 2016
Tietz Jonathan I, Mitchell Douglas A
Abstract excerpt
Natural products (NPs) are the most historically bountiful source of chemical matter for drug development-especially for anti-infectives. With insights gleaned from genome mining, interest in natural product discovery has been reinvigorated. An essential stage in NP discovery is structural elucidation, which sheds light not only on the chemical composition of a molecule but also its novelty, properties, and...
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