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Article

Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets.

Scientific reports - 8 Oct 2015

Lu Junyan, Zeng Hanlin, Liang Zhongjie, Chen Limin, Zhang Liyi, Zhang Hao, Liu Hong, Jiang Hualiang, Shen Bairong, Huang Ming, Geng Meiyu, Spiegel Sarah, Luo Cheng

Abstract excerpt

The connection between inflammation and tumourigenesis has been well established. However, the detailed molecular mechanism underlying inflammation-associated tumourigenesis remains unknown because this process involves a complex interplay between immune microenvironments and epithelial cells. To obtain a more systematic understanding of inflammation-associated tumourigenesis as well as to identify novel...

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PMID: 26446703
DOI: 10.1038/srep14739
PMCID: PMC4597205

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MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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