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Article

Severe epistaxis due to aberrant vasculature in a patient with STAT-1 mutation.

Head & neck - 1 Mar 2016

Chang Michael T, Schwam Zachary G, Hajek Michael A, Paskhover Boris, Judson Benjamin L

Abstract excerpt

BACKGROUND: Signal transducer and activator 1 (STAT-1) mutations are rare and have been implicated in combined immunodeficiency, enhanced tumorigenesis, and vascular defects. METHODS: A 60-year-old woman with a novel STAT-1 mutation and resulting immunodeficiency, squamous cell carcinoma, and vascular disease presented with profuse epistaxis secondary to rupture of an aberrant artery that she developed in part...

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PMID: 26445901
DOI: 10.1002/hed.24165

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