Article
Fishing the targets of myeloid malignancies in the era of next generation sequencing.
Blood reviews - 1 Mar 2016
Shi Xiangguo, He Bai-Liang, Ma Alvin C H, Leung Anskar Y H
Abstract excerpt
Recent advent in next generation sequencing (NGS) and bioinformatics has generated an unprecedented amount of genetic information in myeloidmalignancies. This information may shed lights to the pathogenesis, diagnosis and prognostication of these diseases and provide potential targets for therapeutic intervention. However, the rapid emergence of genetic information will quickly outpace their functional validation...
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