Article
Pharmacogenetic Effect of Complement Factor H Gene Polymorphism in Response to the Initial Intravitreal Injection of Bevacizumab for Wet Age-Related Macular Degeneration.
Ophthalmic research - 1 Jan 2015
Medina Flavio Mac Cord, Alves Lopes da Motta Augusto, Takahashi Walter Y, Carricondo Pedro Carlos, Dos Santos Motta Mario Martins, Melo Monica B, Vasconcellos Jose Paulo C
Abstract excerpt
PURPOSE: To compare the functional and morphological response to the initial intravitreal (IVT) injection of bevacizumab in exudative age-related macular degeneration (AMD) patients with the complement factor H (CFH) gene polymorphism T1277C in the Brazilian population. METHODS: Twenty-five unrelated patients with treatment-naive exudative AMD underwent an IVT injection of 1.25 mg bevacizumab at the initial...
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