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Article

Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa.

The British journal of dermatology - 1 Mar 2016

Lima A L, Karl I, Giner T, Poppe H, Schmidt M, Presser D, Goebeler M, Bauer B

Abstract excerpt

BACKGROUND: The pathogenesis of the chronic inflammatory skin disease hidradenitis suppurativa (HS, also known as acne inversa) involves epidermal alterations such as psoriasiform epidermal hyperplasia and keratin plugging. Keratinocytes are an important source of proinflammatory molecules in inflammatory skin diseases and can be stimulated by interleukin (IL)-17(+) cells. OBJECTIVES: To explore the possible role...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26436522
DOI: 10.1111/bjd.14214

Genes

NLRP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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