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Article

From genotype to phenotype: Are there imaging characteristics associated with lung adenocarcinomas harboring RET and ROS1 rearrangements?

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2015

Plodkowski Andrew J, Drilon Alexander, Halpenny Darragh F, O'Driscoll Dearbhail, Blair Donald, Litvak Anya M, Zheng Junting, Moskowitz Chaya S, Ginsberg Michelle S

Abstract excerpt

INTRODUCTION: Recurrent gene rearrangements are important drivers of oncogenesis in non-small cell lung cancers. RET and ROS1 rearrangements are each found in 1-2% of lung adenocarcinomas and represent distinct molecular subsets. This study assessed the computed tomography (CT) imaging features of patients with RET- and ROS1-rearranged lung cancers. METHODS: Eligible patients included pathologically-confirmed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26424208
DOI: 10.1016/j.lungcan.2015.09.018
PMCID: PMC4907505

Genes

RET
ROS1
EGFR

Provenance

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