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Article

Pre-existing differences in motivation for food and sensitivity to cocaine-induced locomotion in obesity-prone rats.

Physiology & behavior - 1 Dec 2015

Vollbrecht Peter J, Nobile Cameron W, Chadderdon Aaron M, Jutkiewicz Emily M, Ferrario Carrie R

Abstract excerpt

Obesity is a significant problem in the United States, with roughly one third of adults having a body mass index (BMI) over thirty. Recent evidence from human studies suggests that pre-existing differences in the function of mesolimbic circuits that mediate motivational processes may promote obesity and hamper weight loss. However, few preclinical studies have examined pre-existing neurobehavioral differences...

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Identifiers

PMID: 26423787
DOI: 10.1016/j.physbeh.2015.09.022
PMCID: PMC4633384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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