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Article

A single-nucleotide-polymorphism real-time PCR assay for genotyping of Mycobacterium tuberculosis complex in peri-urban Kampala.

BMC infectious diseases - 30 Sept 2015

Wampande Eddie M, Hatzios Stavroula K, Achan Beatrice, Mupere Ezekiel, Nsereko Mary, Mayanja Harriet K, Eisenach Kathleen, Boom W Henry, Gagneux Sebastien, Joloba Moses L

Abstract excerpt

BACKGROUND: Accurate and high-throughput genotyping of Mycobacterium tuberculosis complex (MTBC) may be important for understanding the epidemiology and pathogenesis of tuberculosis (TB). In this study, we report the development of a LightCycler® real-time PCR single-nucleotide-polymorphism (LRPS) assay for the rapid determination of MTBC lineages/sublineages in minimally processed sputum samples from TB...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26423522
DOI: 10.1186/s12879-015-1121-7
PMCID: PMC4590274

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