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Article

[Molecular mechanism of 101A>G and 845G>A mutations of RHD gene responsible for a weak RhD].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2015

Zhang Xu, Sun Changping, Li Jianping

Abstract excerpt

OBJECTIVE: To explore the molecular basis for an individual with a rare weak D phenotype. METHODS: Regular serological assaying and indirect antiglobulin testing (IAT) were performed to characterize the RhD blood group. Mutations of the RHD gene were screened by polymerase chain reaction (PCR), reverse transcription PCR and DNA sequencing. Amplified cDNA product was TA cloned and subjected to haplotype analysis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26418995
DOI: 10.3760/cma.j.issn.1003-9406.2015.05.020

Genes

RHD

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