Article
Association of the five gene related endothelial cell dysfunction polymorphisms with Buerger's disease development.
International angiology : a journal of the International Union of Angiology - 1 Apr 2016
Masoudian Mitra, Fazeli Bahare, Sharebiani Hiva, Rajabnejad Atta'ollah, Ravari Hassan, Akbarin Mohammad M, Dadgarmoghaddam Maliheh
Abstract excerpt
BACKGROUND: The aim of this study was to evaluate the impact of the polymorphisms of four genes related to vascular endothelium dysfunction on the development and outcome of Buerger's disease (BD). The genes studied were eNOS-786 T>C, eNOS894 G>T, ET-1 8000 T>C, PAI-1 4G/5G and ACE I/D. METHODS: Polymerase chain reaction and restriction fragment analysis were used to detect eNOS-786 T>C, eNOS894 G>T, ET-1 8000...
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