Article
Polymorphisms of the NOS3 gene in Tunisian patients with Behçet's disease.
International journal of immunogenetics - 1 Apr 2015
Kallel A, Sbaï M H, Houman M H, Sediri Y, Ouertani D, Smiti Khanfir M, Ben Ghorbel I, Jemaa R, Kaabachi N
Abstract excerpt
Behçet's disease (BD) is a multisystem inflammatory disease characterized by recurrent orogenital ulceration, ocular inflammation and skin lesions. Reduced plasma nitric oxide (NO) levels in patients with BD have been implicated in the development of the endothelial abnormalities and thrombotic complications occurring in these patients. Polymorphisms in the endothelial nitric oxide synthase gene (NOS3) have been...
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