Article
A high-risk phenotype associates with reduced improvement in glycaemia during a lifestyle intervention in prediabetes.
Diabetologia - 1 Dec 2015
Stefan Norbert, Staiger Harald, Wagner Robert, Machann Jürgen, Schick Fritz, Häring Hans-Ulrich, Fritsche Andreas
Abstract excerpt
AIMS/HYPOTHESIS: Lack of reversal of prediabetes (impaired glucose tolerance and/or impaired fasting glucose) to normal glucose regulation (NGR) during a lifestyle intervention is strongly associated with a higher incidence of diabetes later in life. In the Tübingen Lifestyle Intervention Program (TULIP) we hypothesised that an at-risk phenotype may exist at baseline that associates with this nonresponse to the...
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