Article
Phylodynamic reconstruction of the spatiotemporal transmission and demographic history of coxsackievirus B2.
BMC bioinformatics - 21 Sept 2015
Huang Hui-Wen, Chen Yao-Shen, Chen Jeff Yi-Fu, Lu Po-Liang, Lin Yung-Cheng, Chen Bao-Chen, Chou Li-Chiu, Wang Chu-Feng, Su Hui-Ju, Huang Yi-Chien, Shi Yong-Ying, Chen Hsiu-Lin, Sanno-Duanda Bintou, Huang Tsi-Shu, Lin Kuei-Hsiang, Tyan Yu-Chang, Chu Pei-Yu
Abstract excerpt
BACKGROUND: Studies regarding coxsackievirus (CV) tend to focus on epidemic outbreaks, an imbalanced topology is considered to be an indication of acute infection with partial cross-immunity. In enteroviruses, a clear understanding of the characteristics of tree topology, transmission, and its demographic dynamics in viral succession and circulation are essential for identifying prevalence trends in endemic...
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