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Proteomics of Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles

18 Sept 2015

Abstract excerpt

Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis and with endocarditis. Outer membrane vesicles (OMVs) released by this species have been demonstrated to deliver effector proteins such as cytolethal distending toxin (CDT) and leukotoxin (LtxA) into human host cells and to act as triggers of innate immunity upon carriage of NOD1- and...

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PMID: 26381655
DOI: 10.1371/journal.pone.0138591

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