Article
Exploring causal networks underlying fat deposition and muscularity in pigs through the integration of phenotypic, genotypic and transcriptomic data.
BMC systems biology - 16 Sept 2015
Peñagaricano Francisco, Valente Bruno D, Steibel Juan P, Bates Ronald O, Ernst Catherine W, Khatib Hasan, Rosa Guilherme J M
Abstract excerpt
BACKGROUND: Joint modeling and analysis of phenotypic, genotypic and transcriptomic data have the potential to uncover the genetic control of gene activity and phenotypic variation, as well as shed light on the manner and extent of connectedness among these variables. Current studies mainly report associations, i.e. undirected connections among variables without causal interpretation. Knowledge regarding causal...
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