Article
The phenotypes of podocytes and parietal epithelial cells may overlap in diabetic nephropathy.
Kidney international - 1 Nov 2015
Andeen Nicole K, Nguyen Tri Q, Steegh Floor, Hudkins Kelly L, Najafian Behzad, Alpers Charles E
Abstract excerpt
Reversal of diabetic nephropathy (DN) has been achieved in humans and mice, but only rarely and under special circumstances. As progression of DN is related to podocyte loss, reversal of DN requires restoration of podocytes. Here, we identified and quantified potential glomerular progenitor cells that could be a source for restored podocytes. DN was identified in 31 human renal biopsy cases and separated into...
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