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Article

COLQ variant associated with Devon Rex and Sphynx feline hereditary myopathy.

Animal genetics - 1 Dec 2015

Gandolfi Barbara, Grahn Robert A, Creighton Erica K, Williams D Colette, Dickinson Peter J, Sturges Beverly K, Guo Ling T, Shelton G Diane, Leegwater Peter A J, Longeri Maria, Malik Richard, Lyons Leslie A

Abstract excerpt

Some Devon Rex and Sphynx cats have a variably progressive myopathy characterized by appendicular and axial muscle weakness, megaesophagus, pharyngeal weakness and fatigability with exercise. Muscle biopsies from affected cats demonstrated variable pathological changes ranging from dystrophic features to minimal abnormalities. Affected cats have exacerbation of weakness following anticholinesterase dosing, a clue...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Myasthenic Syndromes, Congenital

Source

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Identifiers

PMID: 26374066
DOI: 10.1111/age.12350
PMCID: PMC4637250

Genes

COLQ

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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