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Benzo(a)pyrene inhibits migration and invasion of extravillous trophoblast HTR‐8/SVneo cells via activation of the ERK and JNK pathway

11 Sept 2015

Abstract excerpt

Benzo(a)pyrene (BaP) is a persistent organic pollutant (POP) that is a serious threat to human health. Numerous studies have shown that BaP causes adverse effects in pregnancy, but the mechanism remains unclear. The moderate invasion of trophoblast cells into the endometrium is an important factor during successful embryo implantation. The aim of this study was to investigate the effect and mechanism of BaP on...

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PMID: 26359795
DOI: 10.1002/jat.3227

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