Article
Mutations affecting domain V of the 23S rRNA gene in Helicobacter pylori from Cairo, Egypt.
Journal of chemotherapy (Florence, Italy) - 1 Oct 2016
Ghaith Doaa, Elzahry Mohammad, Mostafa Gehan, Mostafa Sally, Elsherif Rasha, Ramzy Iman
Abstract excerpt
BACKGROUND: Clarithromycin is a main component of the recommended first-line triple therapy for Helicobacter pylori in Egypt. We aimed in our study to investigate the prevalence of clarithromycin-resistant H. pylori strains due to the point mutations at domain V of the H. pylori 23S rRNA among the Egyptian population using the polymerase chain reaction/restricted fragment length polymorphism (PCR/RFLP) assay....
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