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Article

Genetic and microbiome influence on lipid metabolism and dyslipidemia.

Physiological genomics - 1 Feb 2018

Matey-Hernandez Maria Luisa, Williams Frances M K, Potter Tilly, Valdes Ana M, Spector Tim D, Menni Cristina

Abstract excerpt

Disruption in the metabolism of lipids is broadly classified under dyslipidemia and relates to the concentration of lipids in the blood. Dyslipidemia is a predictor of cardio-metabolic disease including obesity. Traditionally, the large interindividual variation has been related to genetic factors and diet. Genome-wide association studies have identified over 150 loci related to abnormal lipid levels, explaining...

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Identifiers

PMID: 29341867
DOI: 10.1152/physiolgenomics.00053.2017
PMCID: PMC5867613

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