A Metagenomic Investigation of the Duodenal Microbiota Reveals Links with Obesity

Abstract excerpt

BACKGROUND: Few studies have tested the small intestine microbiota in humans, where most nutrient digestion and absorption occur. Here, our objective was to examine the duodenal microbiota between obese and normal volunteers using metagenomic techniques. METHODOLOGY/PRINCIPAL FINDINGS: We tested duodenal samples from five obese and five normal volunteers using 16S rDNA V6 pyrosequencing and Illumina MiSeq deep...

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