Article
Molecular and culture-based diagnosis of Clostridium difficile isolates from Côte d'Ivoire after prolonged storage at disrupted cold chain conditions.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Oct 2015
Becker Sören L, Chatigre Justin K, Coulibaly Jean T, Mertens Pascal, Bonfoh Bassirou, Herrmann Mathias, Kuijper Ed J, N'Goran Eliézer K, Utzinger Jürg, von Müller Lutz
Abstract excerpt
BACKGROUND: Although Clostridium difficile is a major cause of diarrhoea, its epidemiology in tropical settings is poorly understood. Strain characterisation requires work-up in specialised laboratories, often after prolonged storage without properly maintained cold chain. METHODS: We screened 298 human faecal samples from Côte d'Ivoire using a rapid test for C. difficile glutamate dehydrogenase (GDH)....
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