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Article

Immunohistochemical Characterization of FacioscapulohumeralMuscular Dystrophy Muscle Biopsies

2 Sept 2015

Abstract excerpt

Background: Posited pathological mechanisms in Facioscapulohumeral Muscular Dystrophy (FSHD) include activation in somatic tissue of normally silenced genes, increased susceptibility to oxidative stress, and induction of apoptosis. Objective: To determine the histopathological changes in FSHD muscle biopsies and compare to possible pathological mechanisms of disease. Methods: We performed a cross-sectional study...

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PMID: 26345300
DOI: 10.3233/jnd-150077

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