Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

JAGGED1 gene variations in Chinese twin sisters with Alagille syndrome.

International journal of clinical and experimental pathology - 1 Jan 2015

Xie Xinbao, Lu Yi, Wang Xiaohong, Wu Bingbing, Yu Hui

Abstract excerpt

Variations in the JAGGED1 gene have been found to cause Alagille syndrome. Nevertheless, no particular hotspots in the gene have been found; any part of the entire coding regions for JAGGED1 may be involved. Twin sisters with jaundice visited our hospital and were diagnosed with Alagille syndrome. The gene variations in their JAGGED1 coding sequences were evaluated by complementary DNA sequencing. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alagille Syndrome
Share to Asian People
Share to Calcium-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diseases in Twins

Share to Intercellular Signaling Peptides and Proteins

Share to Jagged-1 Protein

Share to Membrane Proteins

Share to Serrate-Jagged Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26339425
PMCID: PMC4555753

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

JAGGED1 gene variations in Chinese twin sisters with Alagille syndrome.PMID 26339425Read ↗

Analysis of JAG1 gene variant in Chinese patients with Alagille syndrome.Semantic proximity Read ↗

Mutations in JAGGED1 gene are predominantly sporadic in Alagille syndrome.Semantic proximity Read ↗

Gene symbol: JAG1. Disease: Alagille syndrome.Semantic proximity Read ↗

Gene symbol: JAG1. Disease: Alagille syndrome.Semantic proximity Read ↗

Jagged1 mutations in alagille syndrome.Semantic proximity Read ↗

Alagille syndrome and the Jagged1 gene.Semantic proximity Read ↗

Identification of 36 novel Jagged1 (JAG1) mutations in patients with Alagille syndrome.Semantic proximity Read ↗

JAG1 loss‑of‑function mutations contributed to Alagille syndrome in two Chinese families.Semantic proximity Read ↗

Twelve novel JAG1 gene mutations in Polish Alagille syndrome patients.Semantic proximity Read ↗

Novel JAG1 variants leading to Alagille syndrome in two Chinese casesSemantic proximity Read ↗

JAG1 Mutation Spectrum and Origin in Chinese Children with Clinical Features of Alagille Syndrome.Semantic proximity Read ↗

Clinical and genetic analysis in Chinese children with Alagille syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.