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Article

Genetic interaction of P2X7 receptor and VEGFR-2 polymorphisms identifies a favorable prognostic profile in prostate cancer patients.

Oncotarget - 6 Oct 2015

Solini Anna, Simeon Vittorio, Derosa Lisa, Orlandi Paola, Rossi Chiara, Fontana Andrea, Galli Luca, Di Desidero Teresa, Fioravanti Anna, Lucchesi Sara, Coltelli Luigi, Ginocchi Laura, Allegrini Giacomo, Danesi Romano, Falcone Alfredo, Bocci Guido

Abstract excerpt

VEGFR-2 and P2X7 receptor (P2X7R) have been described to stimulate the angiogenesis and inflammatory processes of prostate cancer. The present study has been performed to investigate the genetic interactions among VEGFR-2 and P2X7R SNPs and their correlation with overall survival (OS) in a population of metastatic prostate cancer patients. Analyses were performed on germline DNA obtained from blood samples and...

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Identifiers

PMID: 26337470
DOI: 10.18632/oncotarget.4926
PMCID: PMC4745689

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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