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Article

Personalized medicine for cystic fibrosis: establishing human model systems.

Pediatric pulmonology - 1 Oct 2015

Mou Hongmei, Brazauskas Karissa, Rajagopal Jayaraj

Abstract excerpt

With over 1,500 identifiable mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that result in distinct functional and phenotypical abnormalities, it is virtually impossible to perform randomized clinical trials to identify the best therapeutics for all patients. Therefore, a personalized medicine approach is essential. The only way to realistically accomplish this is through the...

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Identifiers

PMID: 26335952
DOI: 10.1002/ppul.23233

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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