Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

It Is Not Always Alcohol Abuse--A Transferrin Variant Impairing the CDT Test.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Mar 2016

Zühlsdorf Andrea, Said Michael, Seger Christoph, Park Julien H, Reunert Janine, Rust Stephan, Wada Yoshinao, Grüneberg Marianne, DuChesne Ingrid, Marquardt Thorsten

Abstract excerpt

AIMS: Elevated Carbohydrate-deficient transferrin (CDT) levels are used as a biomarker in order to screen for chronic alcohol abuse. Transferrin (Tf) variants can impair methods to measure elevated CDT levels such as high-performance liquid chromatography (HPLC). We present a Tf variant affecting the second glycosylation site of Tf and the complications it causes in diagnosing alcoholism. METHODS: A blood sample...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Biomarkers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromatography, High Pressure Liquid

Share to SDS gene

Share to Genetic Variation

Share to Mutation

Share to Spectrometry, Mass, Electrospray Ionization

Share to Transferrin

Source

Identifiers

PMID: 26333807
DOI: 10.1093/alcalc/agv099

Genes

SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

It Is Not Always Alcohol Abuse--A Transferrin Variant Impairing the CDT Test.PMID 26333807Read ↗

The novel transferrin E592A variant impairs the diagnostics of congenital disorders of glycosylation.Semantic proximity Read ↗

A novel mutation on the transferrin gene abolishes one N-glycosylation site and alters the pattern of transferrin isoforms, mimicking that observed after excessive alcohol consumption.Semantic proximity Read ↗

Transferrin variants: pitfalls in the diagnostics of Congenital disorders of glycosylation.Semantic proximity Read ↗

Atypical serum transferrin isoform distribution in liver cirrhosis studied by HPLC, capillary electrophoresis and transferrin genotyping.Semantic proximity Read ↗

Carbohydrate-deficient transferrin and chronic alcohol ingestion in subjects with transferrin CD-variants.Semantic proximity Read ↗

Allelic D variants of transferrin in evaluation of alcohol abuse: differential diagnosis by isoelectric focusing-immunoblotting-laser densitometry.Semantic proximity Read ↗

A review of genetic, biological, pharmacological, and clinical factors that affect carbohydrate-deficient transferrin levels.Semantic proximity Read ↗

Determination of carbohydrate-deficient transferrin in human serum using the Bio-Rad %CDT by HPLC test.Semantic proximity Read ↗

Development and multicenter evaluation of the N latex CDT direct immunonephelometric assay for serum carbohydrate-deficient transferrin.Semantic proximity Read ↗

Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.Semantic proximity Read ↗

Monitoring of transferrin isoforms in biological samples by capillary electrophoresis.Semantic proximity Read ↗

[Identification of elevated carbohydrate-deficient transferrin (CDT) serum level as transferrin (Tf)-D-variant by means of isoelectric focusing].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.